undecylenic acid
Sources réglementaires consultées
Indications approuvées
- Teignes du pied, inguinale et corporelle.
Mises en garde cliniques
- Usage externe uniquement ; éviter les yeux. Il n’est pas efficace sur le cuir chevelu ou les ongles ; arrêter et consulter en cas d’irritation ou d’absence d’amélioration à la fin de la période indiquée. — openFDA Undecylenic acid topical 13% set ID 0a7477da-370f-451f-8993-8c675c168696
Grossesse et allaitement
L’étiquette locale concordante ne fournit pas de recommandation spécifique pour la grossesse ou l’allaitement.
Bibliographie récente (PubMed)
Tinea pedis (athlete's foot) is a superficial fungal skin infection caused by dermatophytes, most commonly the anthropophilic dermatophyte Trichophyton rubrum. Clinically, it is characterized mainly by scaling, erythema, and fissure formation, and it may present in three primary forms: interdigital, plantar, and vesiculobullous. The infection is often accompanied by mild pruritus; when fissures develop, burning and pain may also occur. Maceration, fissures, and desquamation of the stratum corneum in the interdigital spaces may serve as entry points for β-haemolytic streptococci, thereby increasing the risk of erysipelas. Another complication is the potential spread of infection to the nails, hands, groin, or other body sites. Tinea pedis is primarily indicated for topical antifungal therapy. Over-the-counter antifungal agents include imidazoles, allylamines, thiocarbamates, and undecylenic acid derivatives. Based on an analysis of clinical studies, their efficacy and duration of treatment have been compared.