flavoxate

Code ATC

G04BD02

Classe thérapeutique

Système génito-urinaire et hormones sexuelles · Antispasmodique urinaire

Formes

Comprimé oral pelliculé de flavoxate à 200 mg

Noms commerciaux

Uronid (ES)

Confiance globale

haute

Sources réglementaires consultées

Soulagement symptomatique de la dysurie, de l’urgence, de la nycturie, de la douleur sus-pubienne, de la pollakiurie et de l’incontinence associées à des affections urologiques.

Obstruction gastro-intestinale ou iléus, hémorragie gastro-intestinale, achalasie, rétention urinaire, glaucome, myasthénie ou hypersensibilité.

Mise en garde majeure · Utiliser avec prudence en cas d’insuffisance rénale, car le métabolite actif est principalement éliminé par le rein. Il peut provoquer une somnolence ou des troubles visuels. — CIMA/AEMPS, ficha técnica 53032

Nausées · Somnolence · Troubles visuels · Vomissements, sécheresse buccale ou dyspepsie

Anaphylaxie ou choc anaphylactique · Rétention urinaire · Ictère ou atteinte hépatique

Il est préférable de l’éviter pendant la grossesse. Ne pas utiliser pendant l’allaitement.

Harnessing Chromone as a Versatile Scaffold for Emerging Biological Applications: Recent Advances and Medicinal Insights.
Kaishap PP, et al. · Chem Rec · 2025 · Pertinence 1/5
Chromones, characterized by a benzo-annulated γ-pyrone core, represent a privileged scaffold, offering a diverse pharmacological spectrum. Clinically approved drugs such as disodium cromoglycate and flavoxate underscore their therapeutic significance. Recent advancements in synthetic strategies have facilitated the development of novel chromone derivatives with improved bioactivity, selectively modulating key molecular targets implicated in cancer, inflammation, diabetes, infectious diseases, and neurodegenerative disorders. Furthermore, their emerging utility as imaging probes and regulators of pharmacologically relevant targets, such as pyridoxal phosphatase (PDXP), highlights their expanding role in modern drug discovery. This review provides a comprehensive overview of recent progress in the identification of bioactive chromone-based natural products and synthetic analogs, emphasizing their therapeutic potential. Additionally, critical innovations in recent synthetic methodologies and targeted therapeutic applications are discussed, reinforcing chromones as a sustainable and multifunctional framework for next-generation drug development.