oxiconazole
Fuentes regulatorias consultadas
Indicaciones aprobadas
- Tratamiento tópico de la tiña del pie, inguinal o corporal y de la pitiriasis versicolor.
Contraindicaciones
Absolutas
- Hipersensibilidad a cualquier componente de la crema.
Advertencias clínicas
- No usar por vía oftálmica ni intravaginal. — openFDA oxiconazole nitrate cream 1% set ID 04477378-cccc-4db3-9e1b-5c1d6a00bd13
- Suspender si aparece sensibilidad o irritación. Evitar el contacto con la nariz, la boca y otras mucosas, y no aplicar bajo oclusión. — openFDA oxiconazole nitrate cream 1% set ID 04477378-cccc-4db3-9e1b-5c1d6a00bd13
Eventos adversos
Comunes (≥1%)
Prurito · Ardor · Irritación
Embarazo y lactancia
Usar durante el embarazo solo si es claramente necesario. El oxiconazol se excreta en leche humana; usar con precaución durante la lactancia.
Bibliografía reciente (PubMed)
Oxime ethers are a class of compounds containing the >C=N-O-R moiety. The presence of this moiety affects the biological activity of the compounds. In this review, the structures of oxime ethers with specific biological activity have been collected and presented, and bactericidal, fungicidal, antidepressant, anticancer and herbicidal activities, among others, are described. The review includes both those substances that are currently used as drugs (e.g., fluvoxamine, mayzent, ridogrel, oxiconazole), as well as non-drug structures for which various biological activity studies have been conducted. To the best of our knowledge, this is the first review of the biological activity of compounds containing such a moiety. The authors hope that this review will inspire scientists to take a greater interest in this group of compounds, as it constitutes an interesting research area.