Simethicone

ATC code

A03AX13

Therapeutic class

Agent for functional gastrointestinal disorders · Antiflatulent (Silicone)

Forms

chewable tablet, softgel, oral drops

Brand names

Aero Red (ES) · Gas-X (US) · Mylanta Gas (US) · Imogas (FR)

Overall confidence

medium

Regulatory sources consulted

aemps-cima-36658
professional-knowledge
RxNorm rxcui 9796 ↗

Approved indications

Symptomatic relief of gas (aerophagia and meteorism) and flatulence.

Contraindications

Absolute

Known hypersensitivity to simethicone. Known or suspected intestinal perforation or obstruction.

Adverse events

Common (≥1%)

constipation · nausea

Rare but serious

hypersensitivity reactions · angioedema

Pregnancy and lactation

Generally considered safe during pregnancy and lactation as it is not systemically absorbed. No adverse effects on the fetus or infant are expected. Consulting a healthcare professional is recommended.