desoximetasone
Regulatory sources consulted
Approved indications
- Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Contraindications
Absolute
- Hypersensitivity to desoximetasone or any component.
Clinical warnings
- Major warning · Use the smallest effective amount for the shortest possible time. Large areas, prolonged use, an impaired skin barrier, and occlusion increase absorption and may cause reversible HPA-axis suppression, Cushing syndrome, hyperglycemia, or glucosuria; children are more susceptible. — DailyMed/openFDA, SPL set ID 0e72952e-8e9f-467a-8191-2bc157087d60
- Avoid eye contact. Stop if irritation or sensitization occurs. Treat any skin infection; if it does not respond promptly, stop the corticosteroid until it is controlled. — DailyMed/openFDA, SPL set ID 0e72952e-8e9f-467a-8191-2bc157087d60
Drug interactions
- ModerateOther corticosteroid-containing products
Mechanism: Simultaneous use may increase total systemic exposure.
Recommendation: Minimize concomitant use and monitor for systemic toxicity.
DailyMed/openFDA, SPL set ID 0e72952e-8e9f-467a-8191-2bc157087d60https://api.fda.gov/drug/label.json?search=openfda.spl_set_id:0e72952e-8e9f-467a-8191-2bc157087d60
Pregnancy and lactation
During pregnancy, use only if potential benefit justifies risk and avoid extensive amounts or prolonged periods. Use cautiously during breastfeeding.